Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP4 | Q02790 | 1/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.52 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28183355 | 0.93 | MEN1 (0.56) | FKBP4SSTR3SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14050124 | 0.92 | FKBP4 (0.57) | FKBP4MMESSTR3SMN1; SMN2MEN1 | |
| SCHEMBL31098846 | 0.92 | FKBP4 (0.51) | FKBP4MMESSTR3SMN1; SMN2MEN1 | |
| SCHEMBL14050095 | 0.91 | FKBP4 (0.60) | FKBP4MMESSTR3SMN1; SMN2MEN1 | |
| SCHEMBL2387136 | 0.87 | SSTR3 (0.57) | SSTR3SMN1; SMN2MEN1KMT2AHDAC8 | |
| SCHEMBL27355181 | 0.87 | SSTR3 (0.57) | SSTR3SMN1; SMN2MEN1KMT2AHDAC8 | |
| SCHEMBL10440798 | 0.85 | SSTR3 (0.56) | SSTR3SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL14027241 | 0.84 | FKBP4 (0.65) | FKBP4 | |
| SCHEMBL14419882 | 0.83 | HDAC8 (0.48) | SSTR3SMN1; SMN2HDAC8HDAC3HDAC4 | |
| SCHEMBL29740041 | 0.83 | SSTR3 (0.59) | SSTR3SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116731-A | Chromogenic protease substrate, calcium ions | BOEHRINGER MANNHEIM GMBH (DE) | 1992-05-26 | — | — | US | disclosed |