Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | FPR1 | P21462 | 4/20 | 0.49 |
| ▸ | FPR2 | P25090 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27355181 | 1.00 | SSTR3 (0.57) | SSTR3SMN1; SMN2KDM1AMAOAMEN1 | |
| SCHEMBL9680449 | 0.87 | FKBP4 (0.55) | SSTR3SMN1; SMN2MEN1KMT2AFPR1 | |
| SCHEMBL29740041 | 0.86 | SSTR3 (0.59) | SSTR3SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL10440798 | 0.86 | SSTR3 (0.56) | SSTR3SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL28183355 | 0.85 | MEN1 (0.56) | SSTR3SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL6243605 | 0.82 | SSTR3 (0.56) | SSTR3SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL31098846 | 0.82 | FKBP4 (0.51) | SSTR3SMN1; SMN2MAOAMEN1KMT2A | |
| SCHEMBL4011349 | 0.82 | F2 (0.64) | KDM1AMAOAHDAC8 | |
| SCHEMBL14050124 | 0.80 | FKBP4 (0.57) | SSTR3SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL29400060 | 0.80 | MMP2 (0.62) | SMN1; SMN2MAOAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7236481-A | — | — | None | — | — | JP | disclosed |
| US-20110236367-A1 | RAT CATHESPIN DIPEPTIDYL PEPTIDASE I (DPPI): CRYSTAL STRUCTURE AND ITS USES | TELENAV, INC. (US) | 2011-09-29 | — | — | US | disclosed |
| US-7736875-B2 | Dipeptidyl peptidase I crystal structure and its uses | PROZYMEX A/S (DK) | 2010-06-15 | — | — | US | disclosed |
| US-20090170953-A1 | INDENTIFICATION OF COMPOUNDS THAT INHIBIT REPLICATION OF HUMAN IMMUNODEFICIENCY VIRUS | TRIPEP AB (SE) | 2009-07-02 | — | — | US | disclosed |
| CN-100382795-C | Glycinamide derivative for inhibiting HIV replication | TRIPEP AB (SE) | 2008-04-23 | — | — | CN | disclosed |
| US-20080076824-A1 | modified glycinamides: Valine-alphahydroxy-glycinamide | CHRONTECH PHARMA AB (SE) | 2008-03-27 | — | — | US | disclosed |
| EP-1317555-B1 | RAT CATHEPSIN, DIPEPTIDYL PEPTIDASE I (DPPI): CRYSTAL STRUCTURE, INHIBITORS AND ITS USES | PROZYMEX AS (DK) | 2007-11-14 | — | — | EP | disclosed |
| EP-1799222-A2 | COMPOUNDS THAT INHIBIT REPLICATION OF HUMAN IMMUNODEFICIENCY VIRUS | TRIPEP AB (SE) | 2007-06-27 | — | — | EP | disclosed |
| EP-1221954-B1 | METHODS FOR IDENTIFYING INHIBITORS OF METHIONINE AMINOPEPTIDASES | UNIV SAINT LOUIS (US) | 2006-09-13 | — | — | EP | disclosed |
| US-20060188920-A1 | enzymatically or synthetically prepared alpha-hydroxyglycinamide inhibit the replication of HIV in human serum | BALZARINI JAN MARIA R | 2006-08-24 | — | — | US | disclosed |
| US-5384247-A | Binding interfering ions, transferases or hydrolases | BOEHRINGER MANNHEIM, GMBH (DE) | 1995-01-24 | — | — | US | disclosed |
| US-5384246-A | Determination of ions in fluids by a process involving displacement of indicator ions | BOEHRINGER MANNHEIM GMBH (DE) | 1995-01-24 | — | — | US | disclosed |
| CN-1085253-A | Dictyostelium dipeptidylaminopeptidase | LILLY CO ELI (US) | 1994-04-13 | — | — | CN | disclosed |
| EP-0504948-A1 | Determination of ions in fluids | THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA (AU) | 1992-09-23 | — | — | EP | disclosed |
| EP-0494705-A2 | Determination of ions in fluids | THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA (AU) | 1992-07-15 | — | — | EP | disclosed |
| EP-0476715-A2 | Method and composition for the determination of chloride ions in fluids | THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA (AU) | 1992-03-25 | — | — | EP | disclosed |
| EP-0471391-A2 | Determination of ions in fluids | THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA (AU) | 1992-02-19 | — | — | EP | disclosed |
| EP-0309525-A1 | DETERMINATION OF IONS IN FLUIDS | THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA (AU) | 1989-04-05 | — | — | EP | disclosed |
| WO-1988008137-A1 | DETERMINATION OF IONS IN FLUIDS | THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA (AU) | 1988-10-20 | — | — | WO | disclosed |
| EP-0286039-A2 | Determination of potassium ions in fluids | THE FLINDERS UNIVERSITY OF SOUTH AUSTRALIA (AU) | 1988-10-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076824-A1 | modified glycinamides: Valine-alphahydroxy-glycinamide | GALE, ENGASE, UGGT1 | SSTR3 4319/4885SMN1; SMN2 4258/4885KDM1A 1318/4885 |
| US-20110236367-A1 | RAT CATHESPIN DIPEPTIDYL PEPTIDASE I (DPPI): CRYSTAL STRUCTURE AND ITS USES | DPP3, DPP7, DPP4 | SSTR3 994/4885SMN1; SMN2 4852/4885KDM1A 3291/4885 |
| US-20090170953-A1 | INDENTIFICATION OF COMPOUNDS THAT INHIBIT REPLICATION OF HUMAN IMMUNODEFICIENCY VIRUS | OGA, ENGASE, GALE | SSTR3 4642/4885SMN1; SMN2 4482/4885KDM1A 1303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.