Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 10/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 4/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682172 | 0.93 | MAPK14 (0.45) | CETPFDFT1MAPK14 | |
| SCHEMBL9785758 | 0.84 | CETP (0.43) | CETPCNR1TRPV1ALDH1A1MAPK14 | |
| SCHEMBL10626804 | 0.81 | FDFT1 (0.43) | CETPFDFT1PPARGPPARA | |
| SCHEMBL9680483 | 0.81 | LTA4H (0.36) | CETPMAPK14PPARG | |
| SCHEMBL10738877 | 0.81 | FDFT1 (0.44) | FDFT1ALDH1A1PPARGPPARA | |
| SCHEMBL10628676 | 0.80 | CETP (0.44) | CETPFDFT1MAPK14PPARG | |
| SCHEMBL10626836 | 0.80 | LTA4H (0.46) | CETPFDFT1PPARG | |
| SCHEMBL10628872 | 0.80 | FDFT1 (0.42) | CETPFDFT1ALDH1A1PPARGPPARA | |
| SCHEMBL10628899 | 0.80 | FDFT1 (0.47) | FDFT1 | |
| SCHEMBL9557901 | 0.79 | MAPK14 (0.48) | CETPFDFT1MAPK14PPARGCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091416-A | INSECTICIDAL COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-02-25 | — | — | US | disclosed |
| EP-0361695-A2 | Insecticidal compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-04-04 | — | — | EP | disclosed |