Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11473446 | 0.85 | CYP2D6 (0.40) | CYP2D6LMNATSHRKMT2ANFKB1 | |
| SCHEMBL31328 | 0.85 | CYP2D6 (0.40) | CYP2D6LMNATSHRKMT2ANFKB1 | |
| SCHEMBL13297030 | 0.84 | CYP2D6 (0.39) | CYP2D6LMNATSHRKMT2ANFKB1 | |
| SCHEMBL25142267 | 0.82 | CYP2D6 (0.38) | CYP2D6LMNATSHRKMT2ANFKB1 | |
| SCHEMBL25475351 | 0.81 | CYP2D6 (0.37) | CYP2D6LMNATSHRKMT2ANFKB1 | |
| SCHEMBL23871042 | 0.81 | CYP2D6 (0.37) | CYP2D6LMNATSHRKMT2ANFKB1 | |
| SCHEMBL7756837 | 0.79 | TSHR (0.36) | CYP2D6LMNATSHRKMT2ANFKB1 | |
| SCHEMBL24117468 | 0.79 | CYP2D6 (0.36) | CYP2D6LMNATSHRKMT2ANFKB1 | |
| SCHEMBL11463228 | 0.79 | CYP2D6 (0.36) | CYP2D6LMNATSHRKMT2ANFKB1 | |
| SCHEMBL6714702 | 0.79 | TSHR (0.37) | CYP2D6LMNATSHRKMT2ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518807-A1 | Piperidine compounds for use as stabilisers for organic materials | CIBA-GEIGY AG (CH) | 1992-12-16 | — | — | EP | disclosed |