Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 7/20 | 0.44 |
| ▸ | THRA | P10827 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680242 | 0.94 | BCHE (0.42) | THRBTHRAMEN1KMT2ABCHE | |
| SCHEMBL10605312 | 0.89 | THRB (0.48) | THRBTHRAMAPTRXFP1MEN1 | |
| SCHEMBL3196140 | 0.87 | MAPT (0.59) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL9679627 | 0.86 | BCHE (0.53) | THRBBCHEACHEALDH1A1 | |
| SCHEMBL3628000 | 0.86 | MAPT (0.62) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL3626621 | 0.86 | HDAC1 (0.42) | THRBTHRAMAPTRXFP1MEN1 | |
| SCHEMBL5180251 | 0.86 | MAPT (0.62) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| SCHEMBL8609378 | 0.86 | MAPT (0.44) | THRBTHRAMAPTRXFP1MEN1 | |
| SCHEMBL5078015 | 0.86 | MAPT (0.62) | MAPTRXFP1HDAC1HDAC2HDAC3 | |
| Hydrochloric Acid SCHEMBL3626622 | 0.86 | MAPT (0.58) | MAPTRXFP1HDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5136013-A | Polyesters | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |
| US-5068300-A | BIFUNCTIONAL STILBENE COMPOUNDS CONTAINING AT LEAST ONE Z-CONFIGURATED STILBENE GROUP, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF POLYMERS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |