SCHEMBL9680702

SCHEMBL9680702

Sc1ccc(C=Cc2ccc(C=Cc3ccc(S)cc3)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.42
NFE2L2 Q16236 3/20 0.39
CYP19A1 P11511 3/20 0.39
MAOB P27338 3/20 0.39
MAOA P21397 2/20 0.39
APP P05067 4/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 3/20 0.38
CYP2C19 P33261 3/20 0.38
HSD17B10 Q99714 3/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA3 P07451 2/20 0.38
CA4 P22748 2/20 0.38
CA6 P23280 2/20 0.38
CA5A P35218 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA13 Q8N1Q1 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL443908 1.00 IDO1 (0.42) IDO1NFE2L2CYP19A1MAOBMAOA
SCHEMBL443909 1.00 IDO1 (0.42) IDO1NFE2L2CYP19A1MAOBMAOA
SCHEMBL9680696 1.00 IDO1 (0.42) IDO1NFE2L2CYP19A1MAOBMAOA
SCHEMBL28525460 0.88 MAOB (0.56) NFE2L2CYP19A1MAOBMAOAMEN1
SCHEMBL13363600 0.87 APP (0.50) IDO1NFE2L2CYP19A1MAOBMAOA
SCHEMBL14646385 0.86 NFE2L2 (0.58) NFE2L2CA1KDM4ECYP1A2CYP3A4
SCHEMBL13429892 0.86 CYP2C19 (0.50) ALDH1A1HPGDCYP2C19KDM4EMEN1
SCHEMBL13478212 0.86 NFE2L2 (0.58) NFE2L2CA1KDM4ECYP1A2CYP3A4
SCHEMBL9680249 0.86 IDO1 (0.68) IDO1NFE2L2MAOBALDH1A1HSD17B10
SCHEMBL18843955 0.86 NFE2L2 (0.61) NFE2L2APPALOX5NQO2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5136013-A Polyesters BAYER AKTIENGESELLSCHAFT (DE) 1992-08-04 US disclosed
EP-0391204-A2 Process for preparing moulded articles of polymers with E-configurated stilbene moieties BAYER AG (DE) 1990-10-10 EP disclosed