Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852426 | 0.81 | PPARG (0.50) | TSHRTDP1L3MBTL1PPARGALDH1A1 | |
| SCHEMBL10903892 | 0.79 | PPARG (0.48) | TSHRTDP1L3MBTL1PPARGALDH1A1 | |
| SCHEMBL7201532 | 0.72 | PPARG (0.37) | TSHRTDP1L3MBTL1PPARGALDH1A1 | |
| SCHEMBL1966607 | 0.72 | TSHR (0.45) | TSHRALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL10598615 | 0.71 | PPARG (0.39) | TSHRTDP1L3MBTL1PPARGALDH1A1 | |
| SCHEMBL10595485 | 0.71 | PPARG (0.39) | TSHRTDP1L3MBTL1PPARGALDH1A1 | |
| SCHEMBL5828433 | 0.71 | PPARG (0.45) | TSHRTDP1L3MBTL1PPARGALDH1A1 | |
| SCHEMBL11363522 | 0.71 | PPARG (0.45) | TSHRTDP1L3MBTL1PPARGALDH1A1 | |
| SCHEMBL4184936 | 0.71 | PPARG (0.45) | TSHRTDP1L3MBTL1PPARGALDH1A1 | |
| SCHEMBL9462288 | 0.71 | PPARG (0.45) | TSHRTDP1L3MBTL1PPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5136013-A | Polyesters | BAYER AKTIENGESELLSCHAFT (DE) | 1992-08-04 | — | — | US | disclosed |
| US-5068300-A | BIFUNCTIONAL STILBENE COMPOUNDS CONTAINING AT LEAST ONE Z-CONFIGURATED STILBENE GROUP, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE PREPARATION OF POLYMERS | BAYER AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |