Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10349155 | 0.91 | ALDH1A1 (0.58) | ALDH1A1TSHRHSD17B10ALOX15TDP1 | |
| Hydrochloric Acid SCHEMBL21837184 | 0.89 | ALDH1A1 (0.55) | ALDH1A1TSHRHSD17B10ALOX15TDP1 | |
| SCHEMBL11489120 | 0.87 | DPP4 (0.42) | KDM4ETDP1DPP4F2 | |
| SCHEMBL61350 | 0.82 | SLC2A1 (0.61) | ALDH1A1KDM4ETSHRHSD17B10ALOX15 | |
| SCHEMBL7110610 | 0.82 | SLC2A1 (0.61) | ALDH1A1KDM4ETSHRHSD17B10ALOX15 | |
| Aminodiphenylmethane SCHEMBL27603626 | 0.81 | DPP4 (0.50) | KDM4ETDP1DPP4F2 | |
| Aminodiphenylmethane SCHEMBL17042856 | 0.81 | TSHR (0.46) | ALDH1A1KDM4ETSHRTDP1MAPK1 | |
| SCHEMBL11480062 | 0.81 | DPP4 (0.61) | KDM4ETSHRDPP4F2 | |
| SCHEMBL11478580 | 0.81 | DPP4 (0.61) | KDM4ETSHRDPP4F2 | |
| SCHEMBL9180847 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KDM4ETSHRHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |