Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL206 | 0.83 | CYP2C19 (0.56) | IDO1CYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7136112 | 0.80 | CYP2C19 (0.54) | IDO1CYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5209412 | 0.80 | CYP2C19 (0.54) | IDO1CYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5209418 | 0.80 | CYP2C19 (0.54) | IDO1CYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2464278 | 0.80 | CYP2C19 (0.55) | IDO1CYP2C19CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL11465830 | 0.78 | CYP2C19 (0.56) | IDO1CYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3078147 | 0.78 | CYP2C19 (0.64) | IDO1CYP2C19CYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL7138153 | 0.78 | CYP2C19 (0.56) | IDO1CYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8541503 | 0.78 | CYP2C19 (0.52) | IDO1CYP2C19CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10993775 | 0.77 | CYP2C19 (0.52) | IDO1CYP2C19CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499521-A1 | Inhibitors of N-myristoyltransferase, their preparation process and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-08-19 | — | — | EP | claimed |
| US-20160346374-A1 | SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 1 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2016-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160346374-A1 | SYNTHETIC VACCINES AGAINST STREPTOCOCCUS PNEUMONIAE TYPE 1 | NEU1, ALG1, CSGALNACT1 | IDO1 455/4885CYP2C19 4363/4885CYP1A2 4231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.