Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | BCAT1 | P54687 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458497 | 0.94 | ALDH1A1 (0.58) | SMN1; SMN2ALDH1A1TSHRMAPK1NPC1 | |
| SCHEMBL9680462 | 0.92 | NPC1 (0.57) | SMN1; SMN2ALDH1A1TSHRMAPK1NPC1 | |
| SCHEMBL10942167 | 0.92 | NPC1 (0.54) | SMN1; SMN2ALDH1A1TSHRMAPK1NPC1 | |
| SCHEMBL10943728 | 0.87 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1TSHRMAPK1NPC1 | |
| SCHEMBL10944254 | 0.87 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1TSHRMAPK1NPC1 | |
| SCHEMBL10943469 | 0.81 | NPC1 (0.55) | SMN1; SMN2ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL10943981 | 0.81 | NPC1 (0.59) | SMN1; SMN2ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL10456874 | 0.79 | ALDH1A1 (0.44) | SMN1; SMN2ALDH1A1TSHRMAPK1KDM4E | |
| SCHEMBL29625805 | 0.79 | KDM4E (0.56) | SMN1; SMN2ALDH1A1TSHRMAPK1NPC1 | |
| SCHEMBL2961648 | 0.79 | KDM4E (0.56) | SMN1; SMN2ALDH1A1TSHRMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170240755-A1 | POLYCYCLIC PHOTOINITIATORS | IGM GROUP B.V. (NL) | 2017-08-24 | — | — | US | disclosed |
| US-20170240755-A1 | POLYCYCLIC PHOTOINITIATORS | IGM GROUP B.V. (NL) | 2017-08-24 | — | — | US | disclosed |
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170240755-A1 | POLYCYCLIC PHOTOINITIATORS | C1R, C9, C5 | SMN1; SMN2 4741/4885ALDH1A1 3469/4885TSHR 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.