Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28283496 | 0.83 | KMT2A (0.47) | KMT2APOLBMEN1GAALMNA | |
| SCHEMBL1850750 | 0.78 | KMT2A (0.43) | KMT2APOLBMEN1GAALMNA | |
| SCHEMBL962782 | 0.72 | LMNA (0.54) | POLBGAALMNASMN1; SMN2TSHR | |
| SCHEMBL5960399 | 0.72 | POLB (0.80) | KMT2APOLBMEN1GAALMNA | |
| SCHEMBL27966258 | 0.71 | LMNA (0.52) | KMT2APOLBMEN1GAALMNA | |
| SCHEMBL3252762 | 0.68 | KMT2A (0.73) | KMT2APOLBMEN1GAALMNA | |
| SCHEMBL1853128 | 0.68 | LMNA (0.53) | KMT2APOLBMEN1GAALMNA | |
| SCHEMBL3778246 | 0.68 | LMNA (0.71) | KMT2AGAALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1853129 | 0.68 | POLB (0.71) | KMT2APOLBMEN1GAALMNA | |
| SCHEMBL28127645 | 0.68 | LMNA (0.58) | KMT2APOLBMEN1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |