SCHEMBL9681225

SCHEMBL9681225

CCCCCC[C@H](C)C(=O)C1(O)C=CC(c2ccccc2)C=C1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
ASAH1 Q13510 1/20 0.36
ACER2 Q5QJU3 1/20 0.36
ACE2 Q9BYF1 1/20 0.36
CNR2 P34972 1/20 0.36
PPARG P37231 3/20 0.36
CA1 P00915 2/20 0.36
KDM4E B2RXH2 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9405732 0.78 DRD3 (0.39)
SCHEMBL9852426 0.76 PPARG (0.50) ALDH1A1CNR2PPARGKDM4EL3MBTL1
SCHEMBL9852458 0.73 OPRM1 (0.39) PPARGCES2CES1
SCHEMBL10440676 0.72 PPARG (0.39) PPARGCES2CES1
SCHEMBL4181876 0.72 PPARG (0.39) PPARGCES2CES1
SCHEMBL4184927 0.72 PPARG (0.39) PPARGCES2CES1
SCHEMBL9746013 0.72 PPARG (0.39) PPARGCES2CES1
SCHEMBL4183418 0.72 PPARG (0.39) PPARGCES2CES1
SCHEMBL4184936 0.72 PPARG (0.45) ALDH1A1PPARGKDM4EKMT2AL3MBTL1
SCHEMBL9462288 0.72 PPARG (0.45) ALDH1A1PPARGKDM4EKMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5128062-A OPTICALLY ACTIVE COMPOUNDS AND LIQUID CRYSTAL COMPOSITIONS CONTAINING SUCH COMPOUNDS WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1992-07-07 US disclosed