Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681230 | 1.00 | NPC1 (0.43) | NPC1KMT2AKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL9681239 | 0.89 | NPC1 (0.46) | NPC1KMT2AKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL9683040 | 0.84 | ERCC5 (0.41) | NPC1KMT2AKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL9683047 | 0.84 | ERCC5 (0.41) | NPC1KMT2AKDM4ESMN1; SMN2L3MBTL1 | |
| SCHEMBL9944266 | 0.83 | HPGD (0.41) | KDM4EHPGDLMNATSHRALDH1A1 | |
| SCHEMBL10387139 | 0.82 | PPARG (0.47) | NPC1KMT2AL3MBTL1TDP1MAPT | |
| SCHEMBL10387140 | 0.82 | PPARG (0.47) | NPC1KMT2AL3MBTL1TDP1MAPT | |
| SCHEMBL7658957 | 0.81 | HPGD (0.46) | NPC1KDM4EL3MBTL1HPGDLMNA | |
| SCHEMBL7658965 | 0.81 | HPGD (0.46) | NPC1KDM4EL3MBTL1HPGDLMNA | |
| SCHEMBL7658954 | 0.81 | HPGD (0.46) | NPC1KDM4EL3MBTL1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147892-A | BENZYL KETONES AND FUNGICIDES CONTAINING THEM | BASF AKTIENGESELLSCHAFT (DE) | 1992-09-15 | — | — | US | disclosed |