Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10387139 | 1.00 | PPARG (0.47) | PPARGKMT2ASLC6A3SLC6A2TDP1 | |
| SCHEMBL10387141 | 0.90 | PPARG (0.49) | PPARGKMT2ASLC6A3SLC6A2TDP1 | |
| SCHEMBL10434828 | 0.87 | TDP1 (0.51) | KMT2ATDP1L3MBTL1TSHRLMNA | |
| SCHEMBL7662861 | 0.84 | ALDH1A1 (0.41) | TDP1L3MBTL1LMNA | |
| SCHEMBL7662857 | 0.84 | ALDH1A1 (0.41) | TDP1L3MBTL1LMNA | |
| SCHEMBL7662937 | 0.82 | LMNA (0.43) | KMT2ATDP1MAPTRAB9APOLB | |
| SCHEMBL7662940 | 0.82 | LMNA (0.43) | KMT2ATDP1MAPTRAB9APOLB | |
| SCHEMBL9681226 | 0.82 | NPC1 (0.43) | KMT2ATDP1L3MBTL1TSHRMAPT | |
| SCHEMBL9262554 | 0.82 | HIF1A (0.50) | TDP1L3MBTL1TSHR | |
| SCHEMBL7172808 | 0.82 | HIF1A (0.50) | TDP1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4952720-A | Ortho-substituted benzyl carboxylates and fungicides which contain these compounds | BASF AKTIENGSELLSCHAFT (DE) | 1990-08-28 | — | — | US | disclosed |