Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680790 | 0.84 | ELANE (0.40) | ELANEPPARAXDH | |
| SCHEMBL10831387 | 0.83 | NPC1 (0.42) | ELANEPPARAFAAHCES1DAGLA | |
| SCHEMBL9682057 | 0.80 | ELANE (0.42) | ELANEPPARAXDH | |
| SCHEMBL9422387 | 0.75 | ELANE (0.39) | ELANEPPARAMAPTEDNRA | |
| SCHEMBL9422377 | 0.74 | ELANE (0.41) | ELANEL3MBTL1 | |
| SCHEMBL9682723 | 0.74 | TLR4 (0.39) | XDHMAPTSMN1; SMN2 | |
| SCHEMBL9681662 | 0.74 | SLC6A2 (0.40) | MAPTTSHRMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2539650 | 0.73 | MEN1 (0.50) | ELANEPPARANPC1RAB9AMAPT | |
| SCHEMBL9680236 | 0.73 | ALDH1A1 (0.50) | MAPTTSHRMAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9565614 | 0.73 | ELANE (0.46) | ELANEFAAHCES1DAGLANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0500934-A1 | ARALKYLOXYAMINE DERIVATIVE AND HERBICIDE | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 1992-09-02 | — | — | EP | disclosed |