Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3374702 | 0.77 | ALDH1A1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL25184627 | 0.77 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1TDP1NLRP3 | |
| SCHEMBL5318797 | 0.76 | — | — | |
| SCHEMBL11398535 | 0.72 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL3372731 | 0.72 | TDP1 (0.33) | ALDH1A1TDP1 | |
| SCHEMBL1341470 | 0.71 | — | — | |
| SCHEMBL6544163 | 0.71 | — | — | |
| SCHEMBL15309765 | 0.70 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL17715736 | 0.70 | ALDH1A1 (0.36) | ALDH1A1TDP1 | |
| SCHEMBL8950674 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |