Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682949 | 0.92 | MAPT (0.67) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL9683242 | 0.88 | MAPT (0.84) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL9683146 | 0.85 | MAPT (0.57) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL13186987 | 0.85 | MAPT (0.61) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL28808881 | 0.85 | MAPT (0.57) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL30984081 | 0.84 | MAPT (0.57) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL25968280 | 0.84 | MAPT (0.57) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL5361493 | 0.84 | MAPT (0.70) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL9682067 | 0.83 | MAPT (0.76) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL2465858 | 0.82 | MAPT (0.75) | MAPTL3MBTL1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |