Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL41854 | 0.81 | TSHR (0.45) | TSHRACHEGABRA1GABRB2ALDH1A1 | |
| SCHEMBL5526684 | 0.78 | TSHR (0.47) | TSHRACHEGABRA1GABRB2ALDH1A1 | |
| SCHEMBL5046947 | 0.76 | TSHR (0.45) | TSHRACHEGABRA1GABRB2ALDH1A1 | |
| SCHEMBL5496813 | 0.74 | GABRA1 (0.58) | TSHRACHEGABRA1GABRB2ALDH1A1 | |
| SCHEMBL8784146 | 0.74 | TSHR (0.50) | TSHRACHEGABRA1GABRB2ALDH1A1 | |
| SCHEMBL6049869 | 0.74 | TSHR (0.50) | TSHRACHEGABRA1GABRB2ALDH1A1 | |
| SCHEMBL12925871 | 0.74 | TSHR (0.50) | TSHRACHEGABRA1GABRB2ALDH1A1 | |
| SCHEMBL1945388 | 0.74 | TSHR (0.50) | TSHRACHEGABRA1GABRB2ALDH1A1 | |
| SCHEMBL31521770 | 0.74 | TSHR (0.50) | TSHRACHEGABRA1GABRB2ALDH1A1 | |
| SCHEMBL30337376 | 0.74 | TSHR (0.50) | TSHRACHEGABRA1GABRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484094-A2 | Azasteroid compounds for the treatment of prostatic hypertrophy, their preparation and use | Sankyo Company Limited (JP) | 1992-05-06 | — | — | EP | disclosed |