Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | CASP6 | P55212 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28065900 | 0.88 | TTR (0.44) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL29386756 | 0.85 | NT5E (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL30867217 | 0.85 | NT5E (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL11429354 | 0.85 | NT5E (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL149843 | 0.85 | NT5E (0.56) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL2332055 | 0.83 | NT5E (0.54) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL11429348 | 0.83 | NT5E (0.54) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL179823 | 0.82 | TTR (0.58) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL29360969 | 0.82 | TTR (0.58) | TTRFABP4CCNA2CDK2MAPK14 | |
| Water SCHEMBL7765550 | 0.80 | TTR (0.56) | TTRFABP4CCNA2CDK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128455-A | WATER-SOLUBLE FIBER-REACTIVE DYES, CONTAINING AN AMINO-SUBSTITUTED 5-TRIAZINE RING WITH A FIBER-REACTIVE GROUP OF THE VINYLSULFONE SERIES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-07 | — | — | US | disclosed |
| EP-0271883-B1 | COLOURED WATER SOLUBLE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-06 | — | — | EP | disclosed |
| EP-0374911-A1 | Water-soluble, fibre-reactive dyes, methods for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-27 | — | — | EP | disclosed |
| EP-0361440-A1 | Water soluble fibre-reactive dyes, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-04 | — | — | EP | disclosed |
| US-4873320-A | COLORFASTNESS; FOR COTTON AND CELLULOSE FIBER MATERIALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-10-10 | — | — | US | disclosed |
| EP-0271883-A2 | Coloured water soluble compounds, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-22 | — | — | EP | disclosed |
| EP-0038453-A2 | Process for the preparation of water soluble phthalocyanine dyestuffs | BAYER AG (DE) | 1981-10-28 | — | — | EP | disclosed |
| US-4268267-A | PRINTING AND DYEING TEXTILES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-19 | — | — | US | disclosed |