Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL631286 | 0.86 | TSHR (0.59) | TSHRALDH1A1THRBTDP1 | |
| SCHEMBL3267819 | 0.82 | TSHR (0.47) | TSHRALDH1A1THRB | |
| SCHEMBL25475956 | 0.82 | TSHR (0.47) | TSHRALDH1A1THRB | |
| SCHEMBL9555207 | 0.80 | TSHR (0.45) | TSHRALDH1A1THRB | |
| SCHEMBL36100 | 0.80 | TSHR (0.45) | TSHRALDH1A1THRB | |
| SCHEMBL4444263 | 0.79 | TSHR (0.46) | TSHRALDH1A1THRBTDP1 | |
| SCHEMBL538063 | 0.79 | TSHR (0.50) | TSHRALDH1A1THRBTDP1 | |
| SCHEMBL3855601 | 0.78 | TSHR (0.44) | TSHRALDH1A1THRBTDP1 | |
| SCHEMBL27146370 | 0.78 | TSHR (0.44) | TSHRALDH1A1THRB | |
| SCHEMBL7628501 | 0.78 | TSHR (0.53) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33997-E | A mixture of collagen and a polymer for shaping to form contact lenses | ALLERGAN, INC. (US) | 1992-07-14 | — | — | US | disclosed |
| EP-0084046-B1 | HYDROGELS OF MODIFIED SOLUBILIZED COLLAGEN | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1987-03-18 | — | — | EP | disclosed |
| EP-0070897-B1 | CONTACT LENSES MADE FROM MODIFIED SYNTHETIC HYDROGELS | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1986-11-26 | — | — | EP | disclosed |
| US-4452925-A | Biologically stabilized compositions comprising collagen as the minor component with ethylenically unsaturated compounds used as contact lenses | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1984-06-05 | — | — | US | disclosed |
| EP-0084046-A4 | HYDROGELS OF MODIFIED SOLUBILIZED COLLAGEN. | NAT PATENT DEV CORP (US) | 1984-01-12 | — | — | EP | disclosed |
| EP-0084046-A1 | HYDROGELS OF MODIFIED SOLUBILIZED COLLAGEN. | NAT PATENT DEV CORP (US) | 1983-07-27 | — | — | EP | disclosed |
| EP-0070897-A4 | Contact lenses made from modified synthetic hydrogels. | NAT PATENT DEV CORP (US) | 1983-06-17 | — | — | EP | disclosed |
| US-4388428-A | DIMENSIONALLY STABLE HYDROGEL | NATIONAL PATENT DEVELOPMENT CORPORATION (US) | 1983-06-14 | — | — | US | disclosed |
| EP-0070897-A1 | Contact lenses made from modified synthetic hydrogels. | NAT PATENT DEV CORP (US) | 1983-02-09 | — | — | EP | disclosed |
| WO-1983000339-A1 | HYDROGELS OF MODIFIED SOLUBILIZED COLLAGEN | NAT PATENT DEV CORP (US) | 1983-02-03 | — | — | WO | disclosed |
| WO-1982002716-A1 | MODIFIED SYNTHETIC HYDROGELS | NAT PATENT DEV CORP (US) | 1982-08-19 | — | — | WO | disclosed |