Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983868 | 0.87 | ALDH1A1 (0.54) | POLBALDH1A1CYP2C19MAPK1MEN1 | |
| SCHEMBL2086090 | 0.84 | SRC (0.60) | POLBALDH1A1CYP2C19MAPK1MEN1 | |
| SCHEMBL9680539 | 0.81 | TDP1 (0.58) | POLBALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL10544088 | 0.80 | ALDH1A1 (0.50) | POLBALDH1A1CYP2C19MAPK1MEN1 | |
| SCHEMBL14198639 | 0.80 | MAPK1 (0.55) | POLBALDH1A1CYP2C19MAPK1MEN1 | |
| SCHEMBL12532569 | 0.79 | MAPK1 (0.62) | POLBALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL28999479 | 0.78 | MAPK1 (0.56) | POLBALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL7992038 | 0.78 | MAPK1 (0.60) | POLBALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL3528826 | 0.77 | ALDH1A1 (0.65) | POLBALDH1A1CYP2C19MAPK1MEN1 | |
| SCHEMBL429356 | 0.77 | ALDH1A1 (0.65) | POLBALDH1A1CYP2C19MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0502594-A1 | Chelates, their metal complexes as well as their use in diagnosis and therapy | INSTITUT FÜR DIAGNOSTIKFORSCHUNG GmbH AN DER FREIEN UNIVERSITÄT BERLIN (DE) | 1992-09-09 | — | — | EP | disclosed |