Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 19/20 | 0.77 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699144 | 0.92 | TBXA2R (0.76) | TBXA2R | |
| SCHEMBL9683030 | 0.92 | TBXA2R (0.78) | TBXA2RAGTR1AGTR2 | |
| SCHEMBL9681962 | 0.92 | TBXA2R (0.78) | TBXA2RAGTR1AGTR2 | |
| SCHEMBL9682056 | 0.91 | TBXA2R (0.80) | TBXA2RAGTR1AGTR2 | |
| SCHEMBL9682478 | 0.90 | TBXA2R (0.78) | TBXA2RAGTR1AGTR2 | |
| SCHEMBL9681886 | 0.89 | TBXA2R (0.68) | TBXA2R | |
| SCHEMBL9681901 | 0.88 | TBXA2R (0.62) | TBXA2R | |
| SCHEMBL9682595 | 0.88 | TBXA2R (0.70) | TBXA2R | |
| SCHEMBL9682945 | 0.87 | TBXA2R (0.62) | TBXA2RAGTR1AGTR2 | |
| SCHEMBL9681429 | 0.87 | TBXA2R (1.00) | TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |
| US-5021443-A | Noval benzimidazole and azabenzimiazole derivatives which are thromboxane receptor antagonists, their methods of preparation and pharmaceutical compositions in which they are present | LABORATOIRES UPSA (FR) | 1991-06-04 | — | — | US | disclosed |