Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 16/20 | 0.80 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.48 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681858 | 0.91 | TBXA2R (0.77) | TBXA2RAGTR1AGTR2 | |
| SCHEMBL9683103 | 0.90 | TBXA2R (0.79) | TBXA2RALOX5AP | |
| SCHEMBL9681962 | 0.90 | TBXA2R (0.78) | TBXA2RAGTR1AGTR2ALOX5AP | |
| SCHEMBL9683125 | 0.89 | TBXA2R (1.00) | TBXA2RALOX5AP | |
| SCHEMBL9683030 | 0.88 | TBXA2R (0.78) | TBXA2RAGTR1AGTR2ALOX5AP | |
| SCHEMBL9682478 | 0.88 | TBXA2R (0.78) | TBXA2RAGTR1AGTR2 | |
| SCHEMBL9681901 | 0.88 | TBXA2R (0.62) | TBXA2RALOX5AP | |
| SCHEMBL9682595 | 0.88 | TBXA2R (0.70) | TBXA2RALOX5AP | |
| SCHEMBL9681897 | 0.87 | TBXA2R (0.78) | TBXA2RALOX5AP | |
| SCHEMBL9683508 | 0.84 | TBXA2R (0.62) | TBXA2RALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | claimed |
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |