SCHEMBL9681914

SCHEMBL9681914

[CH2]CP(C)(C)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11561341 0.75
SCHEMBL11218839 0.72
SCHEMBL10786969 0.70
SCHEMBL11990858 0.67
SCHEMBL7334812 0.67
SCHEMBL84049 0.67
SCHEMBL10621319 0.67 CA2 (0.39)
SCHEMBL5621950 0.65
SCHEMBL4317974 0.64
SCHEMBL1107630 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5134236-A Analgesics, antidepressants, anticonvulsants HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1992-07-28 US disclosed
US-4999356-A Analgesics, antidepressants, anticonvulsants HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1991-03-12 US disclosed
EP-0302423-A2 1-Phenyl-3-(1-piperazinyl)-1h-indazoles, a process and intermediates for their preparation, and the use thereof as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1989-02-08 EP disclosed
EP-0061686-B1 CELLULOSE ETHER AND CELLULOSE MIXTURE ETHER HAVING AT LEAST A PHOSPHOROUS-CONTAINING SUBSTITUENT, AND PROCESS FOR THEIR PREPARATION HOECHST AKTIENGESELLSCHAFT (DE) 1987-08-19 EP disclosed
US-4413121-A Cellulose ethers and cellulose mixed ethers having at least one phosphorus-containing substituent, and process for their manufacture HOECHST AKTIENGESELLSCHAFT (DE) 1983-11-01 US disclosed
EP-0061686-A2 Cellulose ether and cellulose mixture ether having at least a phosphorous-containing substituent, and process for their preparation HOECHST AKTIENGESELLSCHAFT (DE) 1982-10-06 EP disclosed
EP-0044470-A1 Dimethylphosphinyl-alkanephosphonic acids, process for preparing them and their use as cement setting retardants HOECHST AKTIENGESELLSCHAFT (DE) 1982-01-27 EP disclosed