SCHEMBL9681949

SCHEMBL9681949

Nc1ccc(-c2ccccc2OC(F)(F)C(F)(Cl)OC(F)(F)C(F)(F)C(F)(F)F)c(OC(F)(F)C(F)(Cl)OC(F)(F)C(F)(F)C(F)(F)F)c1N

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCN10A Q9Y5Y9 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30396396 0.78 SCN10A (0.42) SCN10A
SCHEMBL9191969 0.74 GLA (0.35)
SCHEMBL4379377 0.64 MPL (0.43) SCN10A
SCHEMBL14743948 0.62 MPL (0.42) SCN10A
SCHEMBL398120 0.62 ALDH1A1 (0.52) SCN10A
SCHEMBL28621084 0.61 ALDH1A1 (0.48)
SCHEMBL7701143 0.60 ALDH1A1 (0.50) SCN10A
SCHEMBL8618190 0.59 ALDH1A1 (0.41)
SCHEMBL2142084 0.59 TSHR (0.42)
SCHEMBL9751705 0.59 KCNN4 (0.38) SCN10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5175367-A Fluorine-containing diamines, polyamides, and polyimides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-29 US disclosed