Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 7/20 | 0.35 |
| ▸ | DPYD | Q12882 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4339951 | 0.74 | — | — | |
| SCHEMBL10920709 | 0.72 | — | — | |
| SCHEMBL16631954 | 0.68 | — | — | |
| SCHEMBL8908 | 0.67 | — | — | |
| SCHEMBL16118350 | 0.67 | AHR (0.33) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL12393541 | 0.66 | — | — | |
| SCHEMBL701812 | 0.66 | NOS3 (0.44) | EGLN2KDM4EALDH1A1 | |
| SCHEMBL3103852 | 0.66 | — | — | |
| SCHEMBL3108893 | 0.66 | — | — | |
| SCHEMBL17185678 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079251-A | Insecticides, pesticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-07 | — | — | US | disclosed |
| EP-0408196-A2 | Pyrazinone derivatives as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-16 | — | — | EP | disclosed |