Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683570 | 0.96 | — | — | |
| Perchlorate SCHEMBL9684019 | 0.79 | NOS2 (0.38) | — | |
| SCHEMBL879167 | 0.77 | NOS2 (0.53) | — | |
| SCHEMBL14932766 | 0.64 | — | — | |
| SCHEMBL8166237 | 0.64 | — | — | |
| Cyclopropanecarboximidamide SCHEMBL1221622 | 0.64 | — | — | |
| SCHEMBL418014 | 0.64 | — | — | |
| Cyclopropanecarboximidamide SCHEMBL25215941 | 0.62 | — | — | |
| Cyclopropanecarboximidamide SCHEMBL275450 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL9292759 | 0.62 | NOS2 (0.93) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484702-A1 | 1-Azoniabicyclo[3.3.0]oct-1(5)-ene salt derivatives and process for the preparation of the same | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1992-05-13 | — | — | EP | disclosed |
| US-5110945-A | 1-azoniabicyclo[3.3.0]oct-1(5)-ene salt derivatives and process for the preparation of the same | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1992-05-05 | — | — | US | disclosed |