Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 10/20 | 0.64 |
| ▸ | HTR1A | P08908 | 8/20 | 0.64 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9683045 | 0.98 | SLC6A2 (0.62) | SLC6A2HTR1ASLC6A4HTR2CSLC6A3 | |
| SCHEMBL28006814 | 0.80 | HTR1A (0.66) | SLC6A2HTR1ASLC6A4HTR2CSLC6A3 | |
| Hydrochloric Acid SCHEMBL16650666 | 0.79 | HTR1A (0.64) | SLC6A2HTR1ASLC6A4HTR2CSLC6A3 | |
| SCHEMBL26712584 | 0.78 | SLC6A2 (0.58) | SLC6A2HTR1ASLC6A4HTR2CSLC6A3 | |
| Hydrochloric Acid SCHEMBL6970223 | 0.76 | SLC6A2 (0.46) | SLC6A2HTR1ASLC6A4SLC6A3 | |
| SCHEMBL11587469 | 0.75 | HTR1A (0.45) | SLC6A2HTR1ASLC6A4 | |
| SCHEMBL20165474 | 0.75 | SLC6A2 (0.74) | SLC6A2HTR1ASLC6A4SLC6A3 | |
| SCHEMBL2299492 | 0.75 | SLC6A2 (0.64) | SLC6A2HTR1ASLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL20165824 | 0.73 | SLC6A2 (0.72) | SLC6A2HTR1ASLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL6971302 | 0.72 | SLC6A2 (0.43) | SLC6A2HTR1ASLC6A4HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | claimed |