SCHEMBL9682048

SCHEMBL9682048

Cc1ccc(CONC(C)C)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.49
NPC1 O15118 2/20 0.49
AGXT P21549 2/20 0.48
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
MMP2 P08253 1/20 0.42
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
MAOB P27338 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
ALDH1A1 P00352 2/20 0.40
IDO1 P14902 1/20 0.38
KCNH2 Q12809 1/20 0.38
ATM Q13315 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
HPGD P15428 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MAPT P10636 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9681267 0.82 CA1 (0.61) RAB9ANPC1AGXTCA1CA2
SCHEMBL9100976 0.81 TSHR (0.46) RAB9ANPC1AGXTMAOBALDH1A1
SCHEMBL29599465 0.71 AGXT (0.54) RAB9ANPC1AGXTCA1CA2
SCHEMBL407132 0.71 AGXT (0.54) RAB9ANPC1AGXTCA1CA2
SCHEMBL9861794 0.70 AGXT (0.58) RAB9ANPC1AGXTCA1CA2
Ammonia Solution, Strong SCHEMBL28605909 0.70 AGXT (0.52) RAB9ANPC1AGXTCA1CA2
SCHEMBL17067471 0.69 RAB9A (0.47) RAB9ANPC1AGXTCA1CA2
SCHEMBL28556461 0.69 RAB9A (0.51) RAB9ANPC1AGXTCA1CA2
SCHEMBL958300 0.69 AGXT (0.64) RAB9ANPC1AGXTCA1CA2
SCHEMBL9617939 0.69 AGXT (0.64) RAB9ANPC1AGXTCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0500934-A1 ARALKYLOXYAMINE DERIVATIVE AND HERBICIDE HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) 1992-09-02 EP disclosed