SCHEMBL9682184

SCHEMBL9682184

Cc1c(C)c(O)c(C)c(Br)c1C

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
HPGD P15428 2/20 0.42
ALOX15 P16050 2/20 0.42
HIF1A Q16665 2/20 0.42
HSD17B10 Q99714 2/20 0.42
TP53 P04637 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
ALOX12 P18054 1/20 0.42
CYP2C19 P33261 1/20 0.42
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
MAPK1 P28482 1/20 0.37
RECQL P46063 1/20 0.37
IMPDH2 P12268 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL205185 0.94 ALDH1A1 (0.41) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL13964603 0.90 ALDH1A1 (0.44) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL13964597 0.90 ALDH1A1 (0.44) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL13964608 0.87 ALDH1A1 (0.46) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL6825540 0.87 ALDH1A1 (0.46) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL11344925 0.84 ALDH1A1 (0.56) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL13964602 0.84 ALDH1A1 (0.50) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL12168389 0.84 ALDH1A1 (0.56) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL13964609 0.81 ALDH1A1 (0.48) ALDH1A1HPGDALOX15HIF1AHSD17B10
SCHEMBL13964600 0.81 CA1 (0.44) ALDH1A1HPGDALOX15HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5098963-A Cresol-formaldehyde resin and 3,5-dibromo-2,4,6-trimethyl phenol for encapsulation of electronics THE DOW CHEMICAL COMPANY (US) 1992-03-24 US claimed
US-5028668-A Encapsulation of Electronics THE DOW CHEMICAL COMPANY (US) 1991-07-02 US claimed
US-4975500-A Encapsulation electronics THE DOW CHEMICAL COMPANY (US) 1990-12-04 US claimed
US-4914185-A FOR ENCAPSULATING ELECTRONIC COMPONENTS THE DOW CHEMICAL COMPANY (US) 1990-04-03 US claimed
EP-0242697-A2 Adducts of metabrominated phenols and polyfunctional epoxides THE DOW CHEMICAL COMPANY (US) 1987-10-28 EP claimed
EP-4074706-A1 DEUTERATED HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME AND COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT EMITTING DEVICE LG Display Co., Ltd. (KR) 2022-10-19 EP disclosed
US-7479531-B2 Copolymer of ethylene and/or propylene; and octen-1-ol,7-octen-1-ol trimethylsilyl ether, octenyl acetate, 5-norbornen-2-yl acetate, 5-norbornen-2-ol and/or 5-norbornen-2-ol trimethylsilyl ether; transition metal catalyst comprising 2-arylazo- or 2-arylphosphazo- phenoxide ligand EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-01-20 US disclosed
US-7479531-B2 Copolymer of ethylene and/or propylene; and octen-1-ol,7-octen-1-ol trimethylsilyl ether, octenyl acetate, 5-norbornen-2-yl acetate, 5-norbornen-2-ol and/or 5-norbornen-2-ol trimethylsilyl ether; transition metal catalyst comprising 2-arylazo- or 2-arylphosphazo- phenoxide ligand EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-01-20 US disclosed
US-7285609-B2 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-23 US disclosed
US-7285609-B2 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-23 US disclosed
EP-1626976-B1 OLEFIN POLYMERIZATION CATALYST SYSTEM EXXONMOBIL CHEM PATENTS INC (US) 2007-10-17 EP disclosed
US-20070197751-A1 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. 2007-08-23 US disclosed
US-20070197751-A1 Olefin polymerization catalyst system useful for polar monomers EXXONMOBIL CHEMICAL PATENTS INC. 2007-08-23 US disclosed
US-5098963-A Cresol-formaldehyde resin and 3,5-dibromo-2,4,6-trimethyl phenol for encapsulation of electronics THE DOW CHEMICAL COMPANY (US) 1992-03-24 US disclosed
US-5028668-A Encapsulation of Electronics THE DOW CHEMICAL COMPANY (US) 1991-07-02 US disclosed
US-4975500-A Encapsulation electronics THE DOW CHEMICAL COMPANY (US) 1990-12-04 US disclosed
US-4914185-A FOR ENCAPSULATING ELECTRONIC COMPONENTS THE DOW CHEMICAL COMPANY (US) 1990-04-03 US disclosed
EP-0242697-A2 Adducts of metabrominated phenols and polyfunctional epoxides THE DOW CHEMICAL COMPANY (US) 1987-10-28 EP disclosed