Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 3/20 | 0.52 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | BRD2 | P25440 | 1/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.46 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10860941 | 0.83 | MAPK1 (0.64) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL10856071 | 0.83 | MAPK1 (0.64) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL25286006 | 0.83 | ALDH1A1 (0.71) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL7455166 | 0.83 | SMN1; SMN2 (0.61) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL16058831 | 0.83 | MAPK1 (0.67) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL10394932 | 0.82 | MEN1 (0.69) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL2793548 | 0.82 | MAPK1 (0.65) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL11400162 | 0.82 | MEN1 (0.69) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL4566277 | 0.81 | MEN1 (0.77) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL9123054 | 0.81 | MAPK1 (0.65) | MAPK1LMNAKDM4EPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082845-A | Gastrointestinal | HOECHST JAPAN LIMITED (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0330031-B1 | THERAPEUTIC AGENTS FOR THE TREATMENT OF PEPTIC ULCER DISEASE | HOECHST JAPAN LIMITED (JP) | 1991-12-11 | — | — | EP | disclosed |
| CN-1014024-B | PROCESS FOR PREPARING PHARMACEUTICALS-FORMULATION | HOECHST AG (DE) | 1991-09-25 | — | — | CN | disclosed |
| EP-0330031-A1 | Therapeutic agents for the treatment of peptic ulcer disease | HOECHST JAPAN LIMITED (JP) | 1989-08-30 | — | — | EP | disclosed |
| CN-85106465-A | A kind of preparation process of pharmaceutical preparation | — | 1986-10-29 | — | — | CN | disclosed |
| US-4576947-A | HYDROXYALKYLXANTHINES, INCREASING CEREBRAL BLOOD FLOW, BRONCHODILATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-03-18 | — | — | US | disclosed |
| US-4515795-A | INSUFFICIENCY OF CEREBRAL BLOOD FLOW | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-05-07 | — | — | US | disclosed |