Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607401 | 0.80 | TSHR (0.35) | GRIK1GRIK2 | |
| SCHEMBL11102174 | 0.77 | — | — | |
| SCHEMBL7636887 | 0.76 | GRIK1 (0.32) | GRIK1 | |
| SCHEMBL7636890 | 0.76 | GRIK1 (0.32) | GRIK1 | |
| SCHEMBL1244582 | 0.75 | GRIK1 (0.44) | GRIK1GRIK2 | |
| SCHEMBL8595697 | 0.75 | GRIK1 (0.44) | GRIK1GRIK2 | |
| SCHEMBL111090 | 0.75 | GRIK1 (0.44) | GRIK1GRIK2 | |
| SCHEMBL156030 | 0.75 | GRIK1 (0.44) | GRIK1GRIK2 | |
| SCHEMBL1245246 | 0.75 | GRIK1 (0.44) | GRIK1GRIK2 | |
| SCHEMBL36412 | 0.75 | GRIK1 (0.44) | GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175319-A | Antiprotozoa agent, useful for treating malaria, theileriosis, coccidiosis and prophylaxix | BURROUGHS WELLCOME CO. (US) | 1992-12-29 | — | — | US | disclosed |
| US-5053432-A | Antiprotozoa agents; treatment of malaria | BURROUGHS WELLCOME CO. (US) | 1991-10-01 | — | — | US | disclosed |
| EP-0123238-B1 | NAPHTHOQUINONE DERIVATIVES | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-06-10 | — | — | EP | disclosed |
| EP-0077550-B1 | 1.4-NAPHTHOQUINONES, METHODS FOR THEIR PREPARATION AND VETERINARY FORMULATIONS THEREOF | THE WELLCOME FOUNDATION LIMITED (GB) | 1985-07-10 | — | — | EP | disclosed |
| US-4485116-A | NAPHTHOQUINONE COMPOUNDS | BURROUGHS WELLCOME CO. | 1984-11-27 | — | — | US | disclosed |
| EP-0123238-A2 | Naphthoquinone derivatives | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-10-31 | — | — | EP | disclosed |
| EP-0077550-A2 | 1.4-Naphthoquinones, methods for their preparation and veterinary formulations thereof | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-04-27 | — | — | EP | disclosed |