Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682067 | 0.92 | MAPT (0.76) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL9683242 | 0.88 | MAPT (0.84) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL17149350 | 0.86 | MAPT (0.71) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL594650 | 0.86 | MAPT (0.61) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL9683008 | 0.83 | MAPT (0.67) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL17152741 | 0.83 | MAPT (0.50) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL9682931 | 0.81 | MAPT (0.58) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL16043208 | 0.81 | MAPT (0.53) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL7335661 | 0.80 | MAPT (0.63) | MAPTL3MBTL1TDP1MEN1KMT2A | |
| SCHEMBL9682949 | 0.80 | MAPT (0.67) | MAPTL3MBTL1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |