Ethylene Glycol

Ethylene Glycol

SCHEMBL9682292

C=C.C=C.C=C.C=C.C=C.COC(=O)OC.OCCO

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
ALDH1A1 P00352 4/20 0.37
HSD17B10 Q99714 1/20 0.35
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35
SI P14410 1/20 0.35
MGAM2 Q2M2H8 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.33
TGFBR1 P36897 1/20 0.33
CYP4A11 Q02928 2/20 0.32
CYP4F2 P78329 1/20 0.32
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
HCAR2 Q8TDS4 1/20 0.32
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
CA2 P00918 2/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL9683861 1.00 TSHR (0.38) TSHRALDH1A1HSD17B10MGAMGAA
Ethylene Glycol SCHEMBL2352840 0.94 TSHR (0.42) TSHRALDH1A1HSD17B10MGAMGAA
Ethylene SCHEMBL2492247 0.87
Ethylene Glycol SCHEMBL9489927 0.81 TSHR (0.38) TSHRALDH1A1HSD17B10MGAMGAA
1,4-Butanediol SCHEMBL28968699 0.81 CYP4A11 (0.42) TSHRALDH1A1HSD17B10SMN1; SMN2CYP4A11
Ethylene Glycol SCHEMBL9487685 0.81 TSHR (0.38) TSHRALDH1A1HSD17B10MGAMGAA
Alcohol SCHEMBL11246505 0.80
Bicarbonate SCHEMBL576692 0.80 ALDH1A1 (0.41) TSHRALDH1A1HSD17B10MGAMGAA
Formaldehyde SCHEMBL27797381 0.79
SCHEMBL4971363 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0476784-A1 Processes for the preparation of ethers UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) 1992-03-25 EP disclosed