Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP14 | P50281 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.44 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.44 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6209324 | 0.85 | MAPT (0.50) | MMP14MAPTMEN1KMT2ANPC1 | |
| SCHEMBL6209327 | 0.85 | MAPT (0.50) | MMP14MAPTMEN1KMT2ANPC1 | |
| SCHEMBL9119582 | 0.83 | MMP14 (0.60) | MMP14MAPTALDH1A1POLBGAA | |
| SCHEMBL8748242 | 0.83 | MMP14 (0.60) | MMP14MAPTALDH1A1POLBGAA | |
| SCHEMBL28728125 | 0.81 | MMP14 (0.70) | MMP14MAPTALDH1A1POLBGAA | |
| SCHEMBL9358069 | 0.81 | MMP14 (0.70) | MMP14MAPTALDH1A1POLBGAA | |
| SCHEMBL9358077 | 0.81 | MMP14 (0.70) | MMP14MAPTALDH1A1POLBGAA | |
| SCHEMBL9551060 | 0.80 | MMP14 (0.61) | MMP14MAPTALDH1A1POLBGAA | |
| SCHEMBL8748245 | 0.80 | MMP14 (0.61) | MMP14MAPTALDH1A1POLBGAA | |
| SCHEMBL9436600 | 0.80 | MMP14 (0.61) | MMP14MAPTALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143577-A | SMOOTH-WALL POLYMERIC CHANNEL AND RIB WAVEGUIDES EXHIBITING LOW OPTICAL LOSS | HOECHST CELANESE CORPORATION (US) | 1992-09-01 | — | — | US | claimed |
| WO-1992013726-A1 | SMOOTH-WALL POLYMERIC CHANNEL AND RIB WAVEGUIDES EXHIBITING LOW OPTICAL LOSS | HOECHST CELANESE CORPORATION (US) | 1992-08-20 | — | — | WO | claimed |