Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.76 |
| ▸ | TTR | P02766 | 6/20 | 0.72 |
| ▸ | DPP4 | P27487 | 2/20 | 0.70 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.63 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29578214 | 1.00 | APP (0.76) | APPTTRDPP4AKR1B10AKR1B1 | |
| SCHEMBL29577718 | 0.94 | APP (0.68) | APPTTRDPP4AKR1B10AKR1B1 | |
| SCHEMBL29577930 | 0.94 | APP (0.68) | APPTTRDPP4AKR1B10AKR1B1 | |
| SCHEMBL20914984 | 0.93 | TTR (0.67) | APPTTRDPP4AKR1B10AKR1B1 | |
| SCHEMBL20914982 | 0.93 | TTR (0.67) | APPTTRDPP4AKR1B10AKR1B1 | |
| SCHEMBL25199144 | 0.93 | TTR (0.67) | APPTTRDPP4AKR1B10AKR1B1 | |
| SCHEMBL1659848 | 0.93 | TTR (0.67) | APPTTRDPP4AKR1B10AKR1B1 | |
| SCHEMBL20941431 | 0.93 | TTR (0.67) | APPTTRDPP4AKR1B10AKR1B1 | |
| SCHEMBL20914981 | 0.93 | TTR (0.67) | APPTTRDPP4AKR1B10AKR1B1 | |
| SCHEMBL20914983 | 0.93 | TTR (0.67) | APPTTRDPP4AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466198-A1 | A lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1992-01-15 | — | — | EP | disclosed |
| EP-0466197-A1 | A lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1992-01-15 | — | — | EP | disclosed |
| EP-0464859-A1 | A lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1992-01-08 | — | — | EP | disclosed |
| EP-0464858-A1 | A lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4733002-A | Lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1988-03-22 | — | — | US | disclosed |
| EP-0163270-A2 | A lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1985-12-04 | — | — | EP | disclosed |