Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.67 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.67 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.67 |
| ▸ | APP | P05067 | 11/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | GMNN | O75496 | 1/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30448962 | 1.00 | TTR (0.67) | TTRAKR1B10AKR1B1APPCYP3A4 | |
| SCHEMBL30610038 | 1.00 | TTR (0.67) | TTRAKR1B10AKR1B1APPCYP3A4 | |
| SCHEMBL20914983 | 1.00 | TTR (0.67) | TTRAKR1B10AKR1B1APPCYP3A4 | |
| SCHEMBL30431823 | 1.00 | TTR (0.67) | TTRAKR1B10AKR1B1APPCYP3A4 | |
| SCHEMBL20914982 | 1.00 | TTR (0.67) | TTRAKR1B10AKR1B1APPCYP3A4 | |
| SCHEMBL25199144 | 1.00 | TTR (0.67) | TTRAKR1B10AKR1B1APPCYP3A4 | |
| SCHEMBL20914984 | 1.00 | TTR (0.67) | TTRAKR1B10AKR1B1APPCYP3A4 | |
| SCHEMBL20941431 | 1.00 | TTR (0.67) | TTRAKR1B10AKR1B1APPCYP3A4 | |
| SCHEMBL20914981 | 1.00 | TTR (0.67) | TTRAKR1B10AKR1B1APPCYP3A4 | |
| SCHEMBL30449303 | 1.00 | TTR (0.67) | TTRAKR1B10AKR1B1APPCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169321-B1 | PROPOLIS AND EXTRACTS THEREOF FOR THE TREATMENT OF SKIN CANCERS AND IMPROVEMENT OF SKIN HEALTH | MANUKA HEALTH NEW ZEALAND LTD (NZ) | 2020-07-15 | — | — | EP | claimed |
| US-20170209499-A1 | Propolis and Extracts Thereof for the Treatment of Skin Cancers and Improvement of Skin Health | MANUKA HEALTH NEW ZEALAND LIMITED (NZ) | 2017-07-27 | — | — | US | claimed |
| EP-3169321-A1 | PROPOLIS AND EXTRACTS THEREOF FOR THE TREATMENT OF SKIN CANCERS AND IMPROVEMENT OF SKIN HEALTH | Manuka Health New Zealand Limited (NZ) | 2017-05-24 | — | — | EP | claimed |
| WO-2016010440-A1 | PROPOLIS AND EXTRACTS THEREOF FOR THE TREATMENT OF SKIN CANCERS AND IMPROVEMENT OF SKIN HEALTH | MANUKA HEALTH NEW ZEALAND LIMITED (NZ) | 2016-01-21 | — | — | WO | claimed |
| US-20240389587-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS | INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (INRAE) (FR) | 2024-11-28 | — | — | US | disclosed |
| EP-4440313-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS | Institut national de recherche pour l'agriculture, L'alimentation et l'environnement (INRAE) (FR) | 2024-10-09 | — | — | EP | disclosed |
| CN-118714927-A | Compositions and methods for controlling phytopathogenic infection | 法国国家农业食品与环境研究院 | 2024-09-27 | — | — | CN | disclosed |
| WO-2023099609-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS | INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (INRAE) (FR) | 2023-06-08 | — | — | WO | disclosed |
| EP-4186367-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS | Institut national de recherche pour l'agriculture, l'alimentation et l'environnement (INRAE) (FR) | 2023-05-31 | — | — | EP | disclosed |
| CN-112569219-B | Medicine for treating artery related diseases and application thereof | 中国科学院上海药物研究所 | 2023-05-02 | — | — | CN | disclosed |
| US-20220395476-A1 | DRUG FOR TREATING ARTERY-RELATED DISEASES, AND USE THEREOF | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2022-12-15 | — | — | US | disclosed |
| EP-4043012-A1 | DRUG FOR TREATING ARTERY-RELATED DISEASES, AND USE THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2022-08-17 | — | — | EP | disclosed |
| WO-2016010440-A1 | PROPOLIS AND EXTRACTS THEREOF FOR THE TREATMENT OF SKIN CANCERS AND IMPROVEMENT OF SKIN HEALTH | MANUKA HEALTH NEW ZEALAND LIMITED (NZ) | 2016-01-21 | — | — | WO | disclosed |
| US-20150246014-A1 | Derivatives of Propane Diyl Dicinnamate | ORX PHARMACEUTICAL CORPORATION (CA) | 2015-09-03 | — | — | US | disclosed |
| US-9061993-B2 | Derivatives of propane diyl dicinnamate | Toronto Institute of Pharmaceutical Technology (CA) | 2015-06-23 | — | — | US | disclosed |
| WO-2014163512-A1 | THERAPEUTIC COMPOSITIONS COMPRISING EXTRACTS OF PROPOLIS AND USES THEREOF | MANUKA HEALTH NEW ZEALAND LIMITED (NZ) | 2014-10-09 | — | — | WO | disclosed |
| EP-2486026-A1 | DERIVATIVES OF DI(PHENYLPROPANOID) GLYCEROL FOR THE TREATMENT OF CANCER | MacGregor, Alexander (CA) | 2012-08-15 | — | — | EP | disclosed |
| CN-102264713-A | Di (phenylpropanoid) glycerol derivatives for the treatment of cancer | — | 2011-11-30 | — | — | CN | disclosed |
| WO-2011041907-A1 | DERIVATIVES OF DI(PHENYLPROPANOID) GLYCEROL FOR THE TREATMENT OF CANCER | MACGREGOR ALEXANDER (CA) | 2011-04-14 | — | — | WO | disclosed |
| US-20110086912-A1 | Derivatives of Propane Diyl Dicinnamate | MACGREGOR ALEXANDER | 2011-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246014-A1 | Derivatives of Propane Diyl Dicinnamate | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, DECR2, DECR1 | TTR 3354/4885AKR1B10 127/4885AKR1B1 84/4885 |
| US-20220395476-A1 | DRUG FOR TREATING ARTERY-RELATED DISEASES, AND USE THEREOF | MYLK, AGT, TNNI3 | TTR 1508/4885AKR1B10 210/4885AKR1B1 159/4885 |
| US-20170209499-A1 | Propolis and Extracts Thereof for the Treatment of Skin Cancers and Improvement of Skin Health | CUTA, DSC1, DACH1 | TTR 2239/4885AKR1B10 2559/4885AKR1B1 3052/4885 |
| US-20110086912-A1 | Derivatives of Propane Diyl Dicinnamate | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, DECR2, DECR1 | TTR 3318/4885AKR1B10 137/4885AKR1B1 88/4885 |
| US-20240389587-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS | XBP1, ERN1, ERN2 | TTR 3033/4885AKR1B10 2183/4885AKR1B1 2435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.