Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | APP | P05067 | 9/20 | 0.56 |
| ▸ | LCK | P06239 | 2/20 | 0.55 |
| ▸ | NQO2 | P16083 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8847575 | 1.00 | IAPP (0.59) | IAPPCYP3A4ALDH1A1RECQLAPP | |
| SCHEMBL9681197 | 0.95 | APP (0.59) | IAPPCYP3A4ALDH1A1RECQLAPP | |
| SCHEMBL8848105 | 0.95 | APP (0.59) | IAPPCYP3A4ALDH1A1RECQLAPP | |
| SCHEMBL30355320 | 0.93 | APP (0.61) | IAPPCYP3A4ALDH1A1RECQLAPP | |
| SCHEMBL28549529 | 0.93 | APP (0.61) | IAPPCYP3A4ALDH1A1RECQLAPP | |
| SCHEMBL9680538 | 0.93 | APP (0.61) | IAPPCYP3A4ALDH1A1RECQLAPP | |
| SCHEMBL8848354 | 0.93 | APP (0.61) | IAPPCYP3A4ALDH1A1RECQLAPP | |
| SCHEMBL28313741 | 0.91 | ALDH1A1 (0.70) | IAPPCYP3A4ALDH1A1RECQLAPP | |
| SCHEMBL28313721 | 0.89 | ALDH1A1 (0.68) | IAPPCYP3A4ALDH1A1RECQLAPP | |
| SCHEMBL6056802 | 0.86 | BACE1 (0.48) | IAPPCYP3A4ALDH1A1RECQLAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466198-A1 | A lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1992-01-15 | — | — | EP | disclosed |
| EP-0466197-A1 | A lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1992-01-15 | — | — | EP | disclosed |
| EP-0464859-A1 | A lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1992-01-08 | — | — | EP | disclosed |
| EP-0464858-A1 | A lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-4733002-A | Lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1988-03-22 | — | — | US | disclosed |
| EP-0163270-A2 | A lipoxygenase inhibitor | GREEN CROSS CORPORATION (JP) | 1985-12-04 | — | — | EP | disclosed |