Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | ADK | P55263 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.43 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5914840 | 0.89 | NISCH (0.41) | NISCHMTORADKADRA2AADRA2B | |
| SCHEMBL14886220 | 0.85 | CSNK1A1 (0.53) | NISCHMTORADKADRA2AADRA2B | |
| SCHEMBL5914869 | 0.85 | NISCH (0.39) | NISCHMTORADKADRA2AADRA2B | |
| SCHEMBL28349336 | 0.80 | NISCH (0.66) | NISCHMTORADKADRA2ACSNK1A1 | |
| SCHEMBL7397776 | 0.80 | MAPT (0.50) | NISCHMTORADKADRA2AADRA2B | |
| SCHEMBL8342759 | 0.78 | ADRA2A (0.46) | NISCHMTORADKADRA2AADRA2B | |
| SCHEMBL3053174 | 0.78 | ADRA2A (0.46) | NISCHMTORADKADRA2AADRA2B | |
| SCHEMBL5914817 | 0.78 | NISCH (0.46) | NISCHMTORADKADRA2AADRA2B | |
| SCHEMBL9622149 | 0.78 | F2RL1 (0.42) | NISCHMTORADKADRA2AADRA2B | |
| SCHEMBL51007 | 0.77 | ADRA2A (0.54) | NISCHMTORADKADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479161-A1 | Synthesis of heterocyclic compounds | EASTMAN CHEMICAL COMPANY (US) | 1992-04-08 | — | — | EP | disclosed |