Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16322812 | 0.86 | MAPT (0.54) | ALDH1A1KMT2APOLBKDM4EL3MBTL1 | |
| SCHEMBL13832650 | 0.85 | GAA (0.66) | ALDH1A1KMT2APOLBKDM4EL3MBTL1 | |
| SCHEMBL26970951 | 0.84 | GAA (0.49) | ALDH1A1KMT2APOLBKDM4EL3MBTL1 | |
| SCHEMBL6003820 | 0.83 | ALDH1A1 (0.48) | ALDH1A1KMT2APOLBKDM4EL3MBTL1 | |
| SCHEMBL3854589 | 0.82 | KMT2A (0.56) | ALDH1A1KMT2APOLBKDM4EGAA | |
| SCHEMBL2219110 | 0.82 | KDM4E (0.49) | ALDH1A1KMT2APOLBKDM4EL3MBTL1 | |
| SCHEMBL30078274 | 0.80 | ALDH1A1 (0.50) | ALDH1A1KMT2APOLBKDM4EL3MBTL1 | |
| SCHEMBL31264133 | 0.78 | POLB (0.46) | ALDH1A1KMT2APOLBKDM4EL3MBTL1 | |
| SCHEMBL21840502 | 0.78 | IRAK4 (0.46) | ALDH1A1KMT2APOLBKDM4EL3MBTL1 | |
| SCHEMBL25703615 | 0.78 | IRAK4 (0.46) | ALDH1A1KMT2APOLBKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334317-B2 | Calcium receptor modulating agents | AMGEN INC. (US) | 2012-12-18 | — | — | US | disclosed |
| US-20110178133-A1 | CALCIUM RECEPTOR MODULATING AGENTS | AMGEN INC. | 2011-07-21 | — | — | US | disclosed |
| US-5082949-A | Plant growth regulators, protective agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-21 | — | — | US | disclosed |
| US-4891057-A | Phenylpyrazolecarboxylic acid derivatives, their preparation, and their use as plant-growth regulators and safeners | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178133-A1 | CALCIUM RECEPTOR MODULATING AGENTS | CASR, CALCR, RYR1 | ALDH1A1 3977/4885KMT2A 4757/4885POLB 4841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.