Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1097050 | 0.81 | PDE4D (0.43) | PDE4BPDE4APDE4CPDE4DHTT | |
| SCHEMBL9833610 | 0.80 | PDE4B (0.40) | PDE4BPDE4APDE4CPDE4DHTT | |
| SCHEMBL8343589 | 0.79 | HTT (0.56) | PDE4BPDE4APDE4CPDE4DHTT | |
| SCHEMBL2773569 | 0.79 | PDE4D (0.41) | PDE4BPDE4APDE4CPDE4DHTT | |
| SCHEMBL17844103 | 0.77 | HTT (0.70) | HTTALDH1A1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL20833878 | 0.76 | HTT (0.40) | PDE4BPDE4APDE4CPDE4DHTT | |
| SCHEMBL9682074 | 0.75 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4DHTT | |
| SCHEMBL24087503 | 0.74 | SMN1; SMN2 (0.45) | HTTALDH1A1SMN1; SMN2CYP2C9CYP2C19 | |
| SCHEMBL6314202 | 0.73 | TP53 (0.56) | HTTALDH1A1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL16177307 | 0.73 | SMN1; SMN2 (0.51) | HTTALDH1A1SMN1; SMN2HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082949-A | Plant growth regulators, protective agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-21 | — | — | US | disclosed |
| US-4891057-A | Phenylpyrazolecarboxylic acid derivatives, their preparation, and their use as plant-growth regulators and safeners | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-02 | — | — | US | disclosed |