Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29185083 | 0.83 | PDE4B (0.43) | PDE4BPDE4AHTTALDH1A1MAPT | |
| SCHEMBL9831108 | 0.80 | PDE4B (0.42) | PDE4BPDE4APDE4CPDE4DCYP1A2 | |
| SCHEMBL2358435 | 0.79 | KMT2A (0.58) | ALDH1A1MAPTCA1CA2CA9 | |
| SCHEMBL9681622 | 0.78 | ALDH1A1 (0.57) | PDE4DHTTALDH1A1MAPTKDM4E | |
| SCHEMBL10469585 | 0.77 | GABRA2 (0.52) | HTTALDH1A1MAPTKDM4EMAPK1 | |
| SCHEMBL8343589 | 0.77 | HTT (0.56) | PDE4BPDE4APDE4CPDE4DHTT | |
| SCHEMBL18338479 | 0.76 | SMN1; SMN2 (0.61) | ALDH1A1MAPTMAPK1TDP1SMN1; SMN2 | |
| SCHEMBL22800293 | 0.76 | HTT (0.46) | PDE4BPDE4DCYP1A2HTTALDH1A1 | |
| SCHEMBL31284343 | 0.76 | GABRB2 (0.42) | PDE4BPDE4APDE4CPDE4DALDH1A1 | |
| SCHEMBL25366957 | 0.75 | ALDH1A1 (0.62) | HTTALDH1A1MAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5082949-A | Plant growth regulators, protective agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-21 | — | — | US | disclosed |
| US-4891057-A | Phenylpyrazolecarboxylic acid derivatives, their preparation, and their use as plant-growth regulators and safeners | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-01-02 | — | — | US | disclosed |