Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.52 |
| ▸ | NT5E | P21589 | 5/20 | 0.52 |
| ▸ | CASP6 | P55212 | 3/20 | 0.47 |
| ▸ | NSD2 | O96028 | 3/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.43 |
| ▸ | ING2 | Q9H160 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL156895 | 0.87 | CYP2C19 (0.50) | ALDH1A1HSD17B10NT5ECASP6NSD2 | |
| SCHEMBL31742544 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HSD17B10NT5ECASP6NSD2 | |
| SCHEMBL1128603 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HSD17B10NT5ECASP6NSD2 | |
| SCHEMBL7516755 | 0.79 | TDP1 (0.57) | ALDH1A1HSD17B10NT5ECASP6NSD2 | |
| SCHEMBL30999 | 0.78 | ING2 (0.48) | ALDH1A1HSD17B10NT5ECASP6NSD2 | |
| SCHEMBL30057851 | 0.78 | ING2 (0.48) | ALDH1A1HSD17B10NT5ECASP6NSD2 | |
| SCHEMBL9242875 | 0.78 | ING2 (0.48) | ALDH1A1HSD17B10NT5ECASP6NSD2 | |
| SCHEMBL29367149 | 0.78 | ING2 (0.48) | ALDH1A1HSD17B10NT5ECASP6NSD2 | |
| SCHEMBL772208 | 0.78 | ING2 (0.48) | ALDH1A1HSD17B10NT5ECASP6NSD2 | |
| SCHEMBL23572660 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HSD17B10NT5ECASP6NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128455-A | WATER-SOLUBLE FIBER-REACTIVE DYES, CONTAINING AN AMINO-SUBSTITUTED 5-TRIAZINE RING WITH A FIBER-REACTIVE GROUP OF THE VINYLSULFONE SERIES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-07 | — | — | US | disclosed |
| EP-0374911-A1 | Water-soluble, fibre-reactive dyes, methods for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-27 | — | — | EP | disclosed |
| US-4912244-A | Vinylsulfonylalkylamino-alkylamines as intermediates for the preparation of fiber-reactive dyes | CIBA-GEIGY CORPORATION (US) | 1990-03-27 | — | — | US | disclosed |
| US-4782140-A | Triazinyl reactive dyes containing additional fiber reactive groups bound through the sulfonylalkylaminoalkylamino bridge | CIBA-GIEGY CORPORATION (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0144766-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | disclosed |
| US-4754023-A | Reactive dyestuffs comprising a triazine moiety and a vinylsulfonyl moiety both being linked by a substituted alkylene bridge member | CIBA-GEIGY CORPORATION (US) | 1988-06-28 | — | — | US | disclosed |
| EP-0159292-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | disclosed |
| EP-0159292-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-10-23 | — | — | EP | disclosed |