SCHEMBL9682713

SCHEMBL9682713

CC(=O)CC(=O)OC1CC(C)(C)N(C)C(C)(C)C1

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.38
MGAM O43451 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.34
ESR1 P03372 1/20 0.34
HSD17B10 Q99714 1/20 0.34
HTT P42858 1/20 0.32
TP53 P04637 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL537637 0.91 KMT2A (0.35) GAAKMT2AMEN1TSHRALDH1A1
SCHEMBL9051338 0.86 TSHR (0.35) GAAKMT2AMEN1TSHRALDH1A1
SCHEMBL11495959 0.86 TSHR (0.35) GAAMGAMSIMGAM2KMT2A
SCHEMBL4408313 0.86 GAA (0.43) GAAMGAMSIMGAM2KMT2A
SCHEMBL18380836 0.85 KMT2A (0.38) GAAKMT2AMEN1TSHRALDH1A1
SCHEMBL13411243 0.84 ALDH1A1 (0.35) GAAKMT2AMEN1TSHRALDH1A1
Suxemerid SCHEMBL2779070 0.84 SMN1; SMN2 (0.39) GAAKMT2AMEN1TSHRALDH1A1
SCHEMBL10171546 0.83 TSHR (0.46) GAAMGAMSIMGAM2KMT2A
SCHEMBL12934427 0.83 KMT2A (0.32) GAAKMT2AMEN1TSHRALDH1A1
SCHEMBL10156172 0.82 CHRM2 (0.37) GAAKMT2AMEN1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0505802-A1 Polyalkylpiperidinyl esters of cyclic beta-ketocarboxylic acids BASF Aktiengesellschaft (DE) 1992-09-30 EP disclosed
US-5124456-A HINDERED AMINE-SUBSTITUTED DIHYDROPYRIDINES AND HEAT/LIGHT STABILIZATION OF POLYMER SUBSTRATES THEREWITH RHONE-POULENC CHIMIE (FR) 1992-06-23 US disclosed
US-4256627-A COMPRISING COMPLEXES OF POLYMERS HAVING UNITS CONTAINING ALKYLPIPERIDINE GROUPS AND NICKEL OR COBALT CARBOXYLATES OR ENOLATES CIBA-GEIGY CORPORATION (US) 1981-03-17 US disclosed
US-4238613-A IMPARTING PHOTOSTABILITY AND OXIDATION AND HEAT RESISTANCE TO PLASTICS CIBA-GEIGY CORPORATION (US) 1980-12-09 US disclosed
US-4154722-A PHOTOSTABILITY CIBA-GEIGY CORPORATION (US) 1979-05-15 US disclosed