Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | RGS12 | O14924 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2736648 | 1.00 | KDM4E (0.57) | KDM4EALDH1A1ADRA2CLMNAADRA2A | |
| SCHEMBL18943970 | 1.00 | KDM4E (0.57) | KDM4EALDH1A1ADRA2CLMNAADRA2A | |
| SCHEMBL359794 | 1.00 | KDM4E (0.57) | KDM4EALDH1A1ADRA2CLMNAADRA2A | |
| SCHEMBL28075639 | 1.00 | KDM4E (0.57) | KDM4EALDH1A1ADRA2CLMNAADRA2A | |
| SCHEMBL4186259 | 1.00 | KDM4E (0.57) | KDM4EALDH1A1ADRA2CLMNAADRA2A | |
| SCHEMBL7125858 | 0.87 | KDM4E (0.46) | KDM4EALDH1A1ADRA2CLMNAADRA2A | |
| SCHEMBL10255083 | 0.82 | AOC3 (0.58) | KDM4EALDH1A1ADRA2CLMNAADRA2A | |
| SCHEMBL14388207 | 0.82 | AOC3 (0.58) | KDM4EALDH1A1ADRA2CLMNAADRA2A | |
| SCHEMBL14387920 | 0.82 | AOC3 (0.58) | KDM4EALDH1A1ADRA2CLMNAADRA2A | |
| SCHEMBL4828396 | 0.82 | AOC3 (0.58) | KDM4EALDH1A1ADRA2CLMNAADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132457-A | Stereospecific synthesis of 2(R)-2-methyl-3-dimethylamino-propiophenone (d-DAMP) | MALLINCKRODT SPECIALTY CHEMICALS COMPANY (US) | 1992-07-21 | — | — | US | disclosed |