Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | RGS12 | O14924 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14388207 | 1.00 | AOC3 (0.58) | AOC3LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL14387920 | 1.00 | AOC3 (0.58) | AOC3LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL14388140 | 1.00 | AOC3 (0.58) | AOC3LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL4828396 | 1.00 | AOC3 (0.58) | AOC3LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL5160626 | 0.87 | AOC3 (0.55) | AOC3LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL6736128 | 0.84 | LMNA (0.59) | AOC3LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL7531733 | 0.83 | AOC3 (0.59) | AOC3LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL1173366 | 0.83 | AOC3 (0.59) | AOC3LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL20644456 | 0.82 | AOC3 (0.40) | AOC3LMNAADRA2CKDM4EADRA2A | |
| SCHEMBL359794 | 0.82 | KDM4E (0.57) | AOC3LMNAADRA2CKDM4EADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230172840-A1 | EPHEDRINE LIQUID FORMULATIONS | FRESENIUS KABI AUSTRIA GMBH (AT) | 2023-06-08 | — | — | US | disclosed |
| US-20170152253-A1 | Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV | Janssen Pharmaceuticals, Inc. (US) | 2017-06-01 | — | — | US | disclosed |
| US-20170101441-A1 | CHEMICAL AND BIOCHEMICAL ADDUCTS AS BIOMARKERS FOR ORGANOPHOSPHATE EXPOSURE | Human BioMolecular Research Foundation (US) | 2017-04-13 | — | — | US | disclosed |
| US-9586893-B2 | Processes and intermediates for preparing a macrocyclic protease inhibitor of HCV | Janssen Pharmaceuticals (US) | 2017-03-07 | — | — | US | disclosed |
| US-9549991-B2 | Chemical and biochemical adducts as biomarkers for organophosphate exposure | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2017-01-24 | — | — | US | disclosed |
| US-20160089439-A1 | Prevention of Illicit Manufacutre of Methamphetamine from Pseudoephedrine Using Food Flavor Excipients | Satara Pharmaceuticals, LLC (US) | 2016-03-31 | — | — | US | disclosed |
| US-9278134-B2 | Dual functioning ionic liquids and salts thereof | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2016-03-08 | — | — | US | disclosed |
| US-20130005976-A1 | Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV | Janssen Pharmaceuticals, Inc. (US) | 2013-01-03 | — | — | US | disclosed |
| US-20120046244-A1 | DUAL FUNCTIONING IONIC LIQUIDS AND SALTS THEREOF | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2012-02-23 | — | — | US | disclosed |
| US-20110236931-A1 | CHEMICAL AND BIOCHEMICAL ADDUCTS AS BIOMARKERS FOR ORGANOPHOSPHATE EXPOSURE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2011-09-29 | — | — | US | disclosed |
| US-7439400-B2 | Amino alcohol ligand and its use in preparation of chiral proparglic tertiary alcohols and tertiary amines via enantioselective addition reaction | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2008-10-21 | — | — | US | disclosed |
| US-7291744-B2 | N-ureidoalkyl-amino compounds as modulators of chemokine receptor activity | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152253-A1 | Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV | HAVCR2, RNASE1, CPB1 | AOC3 277/4885LMNA 2244/4885ADRA2C 1495/4885 |
| US-20230172840-A1 | EPHEDRINE LIQUID FORMULATIONS | EPHA5, EFNA1, EPHA1 | AOC3 2445/4885LMNA 3872/4885ADRA2C 321/4885 |
| US-20120046244-A1 | DUAL FUNCTIONING IONIC LIQUIDS AND SALTS THEREOF | SLC6A6, SLC10A2, CLK2 | AOC3 3911/4885LMNA 2694/4885ADRA2C 4121/4885 |
| US-20160089439-A1 | Prevention of Illicit Manufacutre of Methamphetamine from Pseudoephedrine Using Food Flavor Excipients | PNMT, ACHE, COMT | AOC3 3518/4885LMNA 2720/4885ADRA2C 321/4885 |
| US-20110236931-A1 | CHEMICAL AND BIOCHEMICAL ADDUCTS AS BIOMARKERS FOR ORGANOPHOSPHATE EXPOSURE | AOX1, PTMS, GSTA2 | AOC3 166/4885LMNA 3772/4885ADRA2C 4324/4885 |
| US-20130005976-A1 | Processes and Intermediates for Preparing a Macrocyclic Protease Inhibitor of HCV | HAVCR2, RNASE1, CPB1 | AOC3 277/4885LMNA 2244/4885ADRA2C 1495/4885 |
| US-20170101441-A1 | CHEMICAL AND BIOCHEMICAL ADDUCTS AS BIOMARKERS FOR ORGANOPHOSPHATE EXPOSURE | PTMS, OGFRL1, AOX1 | AOC3 53/4885LMNA 4554/4885ADRA2C 4413/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.