Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | RXRA | P19793 | 2/20 | 0.57 |
| ▸ | RXRB | P28702 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1505169 | 1.00 | MYC (0.58) | MYCNPC1RAB9AKMT2ARXRA | |
| SCHEMBL968770 | 0.92 | NPC1 (0.66) | MYCNPC1RAB9AKMT2ARXRA | |
| SCHEMBL18708443 | 0.90 | MYC (0.56) | MYCNPC1RAB9AKMT2ARXRA | |
| SCHEMBL12798192 | 0.89 | RXRA (0.69) | MYCNPC1RAB9AKMT2ARXRA | |
| SCHEMBL13780844 | 0.88 | NPC1 (0.50) | MYCNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL5207083 | 0.86 | NPC1 (0.59) | MYCNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL967418 | 0.86 | SMN1; SMN2 (0.56) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL12920429 | 0.86 | TP53 (0.57) | NPC1RAB9AKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL969326 | 0.86 | SMN1; SMN2 (0.56) | NPC1RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL5206623 | 0.86 | NPC1 (0.68) | MYCNPC1RAB9AKMT2ARXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101952263-A | Romp-polymerizable electron transport materials based on a bis-oxadiazole moiety | GEORGIA TECH RES INST | 2011-01-19 | — | — | CN | disclosed |
| US-20110009584-A1 | Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-01-13 | — | — | US | disclosed |
| US-20110009584-A1 | Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-01-13 | — | — | US | disclosed |
| EP-2234991-A1 | ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY | Georgia Tech Research Corporation (US) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009080797-A1 | ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080797-A1 | ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009584-A1 | Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety | SLCO1B3, SLCO4C1, SLCO2B1 | MYC 2349/4885NPC1 2287/4885RAB9A 3795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.