Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10918634 | 0.86 | MEN1 (0.34) | MEN1KMT2AHCRTR1HCRTR2 | |
| SCHEMBL9742404 | 0.86 | HCRTR1 (0.43) | MEN1KMT2AL3MBTL1SLC22A12PTGES2 | |
| SCHEMBL9589357 | 0.85 | MEN1 (0.36) | MEN1KMT2ASLC22A12F2 | |
| SCHEMBL9585742 | 0.79 | MEN1 (0.34) | MEN1KMT2ASLC22A12HCRTR1HCRTR2 | |
| SCHEMBL9586542 | 0.79 | KMT2A (0.38) | MEN1KMT2AF2 | |
| SCHEMBL9587373 | 0.78 | CA1 (0.48) | MEN1KMT2AL3MBTL1F2TDP1 | |
| SCHEMBL11053614 | 0.77 | SLC22A12 (0.34) | MEN1KMT2AL3MBTL1SLC22A12PTGES2 | |
| SCHEMBL8441174 | 0.74 | MEN1 (0.36) | MEN1KMT2AL3MBTL1SLC22A12NR1I2 | |
| SCHEMBL9740917 | 0.73 | SMN1; SMN2 (0.38) | MEN1KMT2ASLC22A12F2 | |
| SCHEMBL9729959 | 0.73 | SMN1; SMN2 (0.36) | MEN1KMT2ASLC22A12PTGES2NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499096-A1 | Substituted arylsulfonylaminoguanidinotriazines | BAYER AG (DE) | 1992-08-19 | — | — | EP | disclosed |