Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9730399 | 0.81 | CA1 (0.45) | SMN1; SMN2NPSR1MEN1KMT2AMAPT | |
| SCHEMBL9342205 | 0.74 | GAA (0.39) | SMN1; SMN2SLC22A12TP53GLAMAPT | |
| SCHEMBL9682927 | 0.73 | MEN1 (0.36) | MEN1KMT2ASLC22A12PTGES2NR1I2 | |
| SCHEMBL9742404 | 0.72 | HCRTR1 (0.43) | SMN1; SMN2NPSR1MEN1KMT2ASLC22A12 | |
| SCHEMBL9740917 | 0.70 | SMN1; SMN2 (0.38) | SMN1; SMN2TSHRNPSR1MEN1CYP1A2 | |
| SCHEMBL11053614 | 0.70 | SLC22A12 (0.34) | SMN1; SMN2MEN1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8089115 | 0.69 | CA1 (0.44) | MEN1KMT2AMAPTGAANPC1 | |
| SCHEMBL10876495 | 0.69 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRNPSR1MEN1CYP1A2 | |
| SCHEMBL11111292 | 0.69 | GAA (0.60) | CYP1A2KMT2ATP53GLAMAPT | |
| SCHEMBL10961061 | 0.69 | HCRTR1 (0.41) | SMN1; SMN2MEN1CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5125960-A | Pre- and postemergence | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-30 | — | — | US | disclosed |