Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 18/20 | 0.83 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.52 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683451 | 0.93 | TBXA2R (0.76) | TBXA2R | |
| SCHEMBL9681396 | 0.91 | TBXA2R (1.00) | TBXA2RALOX5AP | |
| SCHEMBL9681409 | 0.89 | TBXA2R (0.66) | TBXA2RALOX5AP | |
| SCHEMBL9683350 | 0.88 | TBXA2R (1.00) | TBXA2RALOX5AP | |
| SCHEMBL9682959 | 0.86 | TBXA2R (1.00) | TBXA2R | |
| SCHEMBL9681374 | 0.84 | TBXA2R (0.88) | TBXA2R | |
| SCHEMBL9683255 | 0.82 | TBXA2R (1.00) | TBXA2R | |
| SCHEMBL9682396 | 0.81 | TBXA2R (0.58) | TBXA2RALOX5AP | |
| SCHEMBL9681382 | 0.80 | TBXA2R (1.00) | TBXA2RALOX5AP | |
| SCHEMBL9681381 | 0.79 | TBXA2R (0.79) | TBXA2RALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | claimed |
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |